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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Clontech/Tet-tTS transcriptional silencer/20 ug/631011
产品编号:631011
市  场 价:¥0.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:待定
品      牌: Clontech
公      司:Clontech
公司分类:
Clontech/Tet-tTS transcriptional silencer/20 ug/631011
商品介绍

Tet-tTS transcriptional silencer

pTet-tTS expresses the tetracycline/doxycycline-controlled transcription silencer (tTS), which is a fusion of the tet repressor protein (TetR) with a KRAB silencing domain. tTS can be used to significantly lower the basal expression from first-generation Tet systems, but is not required forTet-On 3G or Tet-One systemssince the basal expression is typically very low.

pTet-tTS expresses the tetracycline/doxycycline-controlled transcription silencer (tTS), which is a fusion of the tet repressor protein (TetR) with a KRAB silencing domain. tTS can be used to significantly lower the basal expression from first-generation Tet systems, but is not required for Tet-On 3G or Tet-One systems since the basal expression is typically very low.

In the absence of doxycycline, tTS binds to the tet-operator sequences within TRE promoters, silencing gene expression. Upon addition of doxycycline, tTS undergoes a conformational change that causes its release from the promoter, to be replaced by the Tet-On transactivator.

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品牌介绍

美国Clontech公司是一家专门致力于基因工程及蛋白质工程领域研究用产品的研发和生产的专业公司。公司产品涉及PCR产品、RT-PCR产品、cDNA文库构建、基因克隆、基因表达、基因分析、蛋白质技术等诸多领域。产品种类多达2000多种。Clontech公司拥有多种独立知识产权产品,其强大的科研实力和完善的质量管理体系(ISO9001)为Clontech产品的良好品质提供了可靠保障。

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